Kynurenic Acid

Title: Kynurenic Acid
CAS Registry Number: 492-27-3
CAS Name: 4-Hydroxy-2-quinolinecarboxylic acid
Additional Names: 4-hydroxyquinaldic acid
Molecular Formula: C10H7NO3
Molecular Weight: 189.17
Percent Composition: C 63.49%, H 3.73%, N 7.40%, O 25.37%
Literature References: Found in the urine of some animals as a metabolic product of tryptophan; its excretion is stepped up in avitaminoses B1, B2 and B6. Isoln and syntheses: Späth, Monatsh. Chem. 42, 89 (1921); Besthorn, Ber. 54, 1330 (1921). Alternate syntheses: Benassi, Gazz. Chim. Ital. 91, 1097 (1961); Wald, Joullie, J. Org. Chem. 31, 3369 (1966); Jordanides, Ann. 729, 244 (1969).
Properties: Yellow needles, mp 282-283°. Soly in water: about 0.9% at 100°. Sol in hot alc. Insol in ether.
Melting point: mp 282-283°
Derivative Type: Methyl ester
Molecular Formula: C11H9NO3
Molecular Weight: 203.19
Percent Composition: C 65.02%, H 4.46%, N 6.89%, O 23.62%
Properties: Yellow crystals, mp 224°. Cf. xanthurenic acid.
Melting point: mp 224°
Use: In nutrition studies, specifically in vitamin B deficiency diseases.
L-2-Oxo-4-thiazolidinecarboxylic acid Labetalol Laccaic Acid Lachesine Lacidipine