Oxeladin

Title: Oxeladin
CAS Registry Number: 468-61-1
CAS Name: a,a-Diethylbenzeneacetic acid 2-[2-(diethylamino)ethoxy]ethyl ester
Additional Names: 2-ethyl-2-phenylbutyric acid 2-(2-diethylaminoethoxy)ethyl ester; 2-(2-diethylaminoethoxy)ethyl a,a-diethylphenylacetate; a,a-diethylphenylacetic acid 2-(2-diethylaminoethoxy)ethyl ester
Molecular Formula: C20H33NO3
Molecular Weight: 335.48
Percent Composition: C 71.60%, H 9.91%, N 4.18%, O 14.31%
Literature References: Prepn: V. Petrow et al., J. Pharm. Pharmacol. 10, 40 (1958); eidem, US 2885404 (1959 to Brit. Drug Houses).
Properties: Yellow oil with an acrid odor and bitter taste. bp0.5 150°; bp0.1 140°. Soluble in dil HCl, ethanol, acetone, ether, toluene; practically insol in water. Stable in acids, unstable in alkalies. Non-hygroscopic.
Boiling point: bp0.5 150°; bp0.1 140°
Derivative Type: Citrate
CAS Registry Number: 52432-72-1
Trademarks: Pectamol (BDH); Pectamon; Paxeladine (Beaufour)
Molecular Formula: C20H33NO3.C6H8O7
Molecular Weight: 527.60
Percent Composition: C 59.19%, H 7.83%, N 2.65%, O 30.32%
Properties: Small needles from ethyl acetate, mp 90-91°. Sol in water.
Melting point: mp 90-91°
Therap-Cat: Antitussive.
Keywords: Antitussive.
Oxendolone Oxenin Oxethazaine Oxetorone Oxfendazole

Oxeladin
Oxeladin.png
Systematic (IUPAC) name
2-(2-diethylaminoethoxy)ethyl 2-ethyl-2-phenyl-butanoate
Clinical data
AHFS/Drugs.com International Drug Names
Legal status  ?
Identifiers
CAS number 468-61-1 N
ATC code R05DB09
PubChem CID 4619
DrugBank DB04822
ChemSpider 4458 YesY
UNII SNC1080T5Y YesY
KEGG D08310 YesY
ChEMBL CHEMBL1500276 N
Chemical data
Formula C20H33NO3 
Mol. mass 335.481 g/mol
 N (what is this?)  (verify)

Oxeladin is a cough suppressant. It is a highly potent and effective drug used to treat all types of cough of various etiologies. It is not related to opium or its derivatives, so treatment with oxeladin is free of risk of dependence or addiction. Oxeladin has none of the side effects (such as hypnosis, respiratory depression, tolerance, constipation and analgesia) which are present when common antitussives, such as codeine and its derivatives, are used. It may be used at every age, as well as in patients with heart disease, since it has a high level of safety and a great selectivity to act on the bulbar centre of cough.