Oxibendazole

Title: Oxibendazole
CAS Registry Number: 20559-55-1
CAS Name: (5-Propoxy-1H-benzimidazol-2-yl)carbamic acid methyl ester
Additional Names: 5-propoxy-2-benzimidazolecarbamic acid methyl ester; 5-propoxy-2-(carbomethoxyamino)benzimidazole
Manufacturers' Codes: SKF-30310
Trademarks: Anthelcide EQ (Pfizer); Equitac (Pfizer)
Molecular Formula: C12H15N3O3
Molecular Weight: 249.27
Percent Composition: C 57.82%, H 6.07%, N 16.86%, O 19.26%
Literature References: Prepn: GB 1123317 corresp to P. P. Actor, J. F. Pagano, US 3574845 (1968, 1971 both to SK & F). Comparative anthelmintic effects in mice: C. S. Karunakaron, D. A. Denham, J. Parasitol. 66, 929 (1980). Clinical studies in foals and horses: J. H. Drudge et al., Am. J. Vet. Res. 42, 526 (1981); E. T. Lyons et al., ibid. 685; D. K. Hass et al., ibid. 43, 534 (1982).
Properties: Cryst, mp 230-230.5°.
Melting point: mp 230-230.5°
Therap-Cat-Vet: Anthelmintic.
Oxiconazole Nitrate Oxidimethiin Oxidized Cellulose Oxidronic Acid Oxiniacic Acid

Oxibendazole
Oxibendazole.png
Systematic (IUPAC) name
methyl N-(6-propoxy-1H-benzimidazol-2-yl)carbamate
Clinical data
AHFS/Drugs.com International Drug Names
Legal status Veterinary use only
Identifiers
CAS number 20559-55-1 YesY
ATCvet code QP52AC07
PubChem CID 4622
UNII 022N12KJ0X YesY
KEGG D05293 YesY
Chemical data
Formula C12H15N3O3 
Mol. mass 249.26 g/mol
 YesY (what is this?)  (verify)

Oxibendazole is a benzimidazole drug that is used to protect against roundworms, strongyles, threadworms, pinworms and lungworm infestations in horses and some domestic pets. It is usually white to yellowish in appearance, and may take the form of a powder or a tablet.

Oxibendazole can be synthesized from acetominophen by the following route:[1]

Oxibendazole scheme.png