Title: Oxophenarsine Hydrochloride
CAS Registry Number: 538-03-4
CAS Name: 2-Amino-4-arsenosophenol hydrochloride
Additional Names: 3-amino-4-hydroxyphenyl arsinoxide hydrochloride
Manufacturers' Codes: Ehrlich 5; Arseno 39
Trademarks: Arsenoxide; Mapharsen (Parke-Davis); Mapharside; Mapharsal; Fontarsan; Arsenosan; Oxiarsolan
Molecular Formula: C6H7AsClNO2
Molecular Weight: 235.50
Percent Composition: C 30.60%, H 3.00%, As 31.81%, Cl 15.05%, N 5.95%, O 13.59%
Literature References: Ref: G. W. Raiziss, J. L. Gavron, Organic Arsenical Compounds (Chem. Catalog Co., New York, 1923), pp 136-137; Scott, Tullar, CA 405532 (1942 to Parke, Davis).
Properties: Hygroscopic, white or nearly white, powder contg ½ mole ethanol. Readily sol in water, methanol, ethanol, in solns of alkali hydroxides and carbonates, in dil mineral acids. Sparingly sol in glacial acetic acid. Practically insol in acetone, ether. The aq soln is acid to litmus or methyl red, but alkaline to Congo red. Solns darken on exposure to air. Usually marketed mixed with buffering agents to render its soln physiologically compatible with human blood.
Therap-Cat: Antiprotozoal (Trypanosoma).
Therap-Cat-Vet: Has been used as an antirickettsial.
Keywords: Antiprotozoal (Trypanosoma).