Oxypertine

Title: Oxypertine
CAS Registry Number: 153-87-7
CAS Name: 5,6-Dimethoxy-2-methyl-3-[2-(4-phenyl-1-piperazinyl)ethyl]-1H-indole
Additional Names: 1-[2-(5,6-dimethoxy-2-methyl-3-indolyl)ethyl]-4-phenylpiperazine
Manufacturers' Codes: Win-18501-2
Trademarks: Equipertine; Forit; Integrin (formerly) (Sterling)
Molecular Formula: C23H29N3O2
Molecular Weight: 379.50
Percent Composition: C 72.79%, H 7.70%, N 11.07%, O 8.43%
Literature References: Prepn: Archer et al., J. Am. Chem. Soc. 84, 1306 (1962).
Therap-Cat: Antidepressant.
Keywords: Antidepressant; Bicyclics.
Oxyphenbutazone Oxyphencyclimine Oxyphenisatin Acetate Oxyphenonium Bromide Oxypinocamphone

Oxypertine
Oxypertine.png
Systematic (IUPAC) name
5,6-dimethoxy-2-methyl-3-[2-(4-phenylpiperazin-1-yl)ethyl]-1H-indole
Clinical data
AHFS/Drugs.com International Drug Names
Legal status Prescription only
Routes Oral
Identifiers
CAS number 153-87-7 YesY
ATC code N05AE01
PubChem CID 4640
UNII 5JGL4G25R7 YesY
KEGG D01219 YesY
Chemical data
Formula C23H29N3O2 
Mol. mass 379.49 g/mol
 YesY (what is this?)  (verify)

Oxypertine (Equipertine, Forit, Integrin, Lanturil, Lotawin, Opertil) is an antipsychotic used in the treatment of schizophrenia.[1] Chemically, it is an indole derivative similarly to molindone and a member of the phenylpiperazine class.[2] Like reserpine and tetrabenazine, oxypertine depletes catecholamines, though not serotonin, possibly underlying its neuroleptic efficacy.[3]