Pyrrocaine

Title: Pyrrocaine
CAS Registry Number: 2210-77-7
CAS Name: N-(2,6-Dimethylphenyl)-1-pyrrolidineacetamide
Additional Names: 1-pyrrolidineaceto-2¢,6¢-xylidide; 2-(1-pyrrolidinyl)-2¢,6¢-acetoxylidide; 1-pyrrolidinoaceto-2,6-dimethylanilide
Manufacturers' Codes: EN-1010; NSC-52644
Trademarks: Endocaine (Endo); Dynacaine
Molecular Formula: C14H20N2O
Molecular Weight: 232.32
Percent Composition: C 72.38%, H 8.68%, N 12.06%, O 6.89%
Literature References: Prepn: Schlesinger, Gordon, US 2813861 (1957 to Endo); Löfgren et al., Acta Chem. Scand. 11, 1724 (1957).
Properties: Crysts from hexane or petr ether + dibutyl ether, mp 83°.
Melting point: mp 83°
Derivative Type: Hydrochloride
CAS Registry Number: 2210-64-2
Molecular Formula: C14H20N2O.HCl
Molecular Weight: 268.78
Percent Composition: C 62.56%, H 7.88%, N 10.42%, O 5.95%, Cl 13.19%
Properties: Crystals from isopropanol, mp 205°. Soluble in water, alcohol, isopropyl alcohol. Practically insol in chloroform, ether.
Melting point: mp 205°
Therap-Cat: Anesthetic (local).
Keywords: Anesthetic (Local).
Pyrrolidine Pyrrolnitrin Pyrrolysine Pyruvate Decarboxylase Pyruvic Acid