Ronidazole

Title: Ronidazole
CAS Registry Number: 7681-76-7
CAS Name: 1-Methyl-5-nitroimidazole-2-methanol carbamate (ester)
Additional Names: carbamic acid (1-methyl-5-nitroimidazol-2-yl)methyl ester; 1-methyl-2-[(carbamoyloxy)methyl]-5-nitroimidazole; (1-methyl-5-nitroimidazole-2-yl)methyl carbamate; MCMN
Trademarks: Ridzol (Merck & Co.)
Molecular Formula: C6H8N4O4
Molecular Weight: 200.15
Percent Composition: C 36.01%, H 4.03%, N 27.99%, O 31.97%
Literature References: Prepn and antiprotozoal activity: NL 6609552; NL 6609553 (both 1967 to Merck & Co.), C.A. 67, 54123u, 11487y (1967); Verdi; Kollonitsch, US 3450710; US 3459764 (both 1969 to Merck & Co.).
Properties: Pale yellow crystals, mp 167-169°. Soly in water (at pH 6.5) ~2.9 mg/ml at room temp. More sol in acid solns. Unstable in alkaline solns. pKa 1.2. Freely sol in acetone. Sol in methanol, ethanol, chloroform and ethyl acetate.
Melting point: mp 167-169°
pKa: pKa 1.2
Therap-Cat-Vet: Antimicrobial.
Ronifibrate Ronnel Roquinimex Rosaprostol Rosaramicin

Ronidazole
Ronidazole.svg
Identifiers
CAS number 7681-76-7 YesY
PubChem 5094
ChemSpider 4915
UNII E01R4M1063
ChEMBL CHEMBL290299
ATCvet code QP51AA08
Jmol-3D images Image 1
Properties
Molecular formula C6H8N4O4
Molar mass 200.15 g mol−1
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Ronidazole is an antiprotozoal agent used in veterinary medicine for the treatment of histomoniasis and swine dysentery.[1][2][3] It may also have use for the treatment of Tritrichomonas foetus infection in cats.[4]