Ronifibrate

Title: Ronifibrate
CAS Registry Number: 42597-57-9
CAS Name: 3-Pyridinecarboxylic acid 3-[2-(4-chlorophenoxy)-2-methyl-1-oxopropoxy]propyl ester
Additional Names: 3-(nicotinoyloxy)propyl p-chlorophenoxyisobutyrate; 3-[a-(p-chlorophenoxy)isobutyryloxy]propyl nicotinate
Manufacturers' Codes: I-612
Trademarks: Cloprane (Luitpold)
Molecular Formula: C19H20ClNO5
Molecular Weight: 377.82
Percent Composition: C 60.40%, H 5.34%, Cl 9.38%, N 3.71%, O 21.17%
Literature References: Diester of clofibric and nicotinic acids, q.q.v. Prepn: Y. Hirata et al., JP Kokai 73 40777 (1973 to Yamanouchi), C.A. 79, 66180w (1973); H. Shindo et al., JP Kokai 74 30377 (1974 to Kowa Pharm.), C.A. 81, 135984s (1974). Clinical trial in hyperdyslipidemia: A. Bucalossi et al., Clin. Ter. 89, 127 (1979). Efficacy and tolerability: G. Buzzelli et al., ibid. 251.
Properties: LD50 orally in mice: 4.08 g/kg (Bucalossi).
Toxicity data: LD50 orally in mice: 4.08 g/kg (Bucalossi)
Therap-Cat: Antilipemic.
Keywords: Antilipemic; Fibrates.
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Ronifibrate
Ronifibrate.svg
Systematic (IUPAC) name
3-{[2-(4-chlorophenoxy)-2-methylpropanoyl]oxy}propyl nicotinate
Clinical data
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Identifiers
CAS number 42597-57-9 N
ATC code C10AB07
PubChem CID 68671
ChemSpider 61925 YesY
UNII W86I18X716 YesY
ChEMBL CHEMBL153983 YesY
Synonyms 3-[(pyridin-3-yl)carbonyloxy]propyl 2-(4-chlorophenoxy)-2-methylpropanoate
Chemical data
Formula C19H20ClNO5 
Mol. mass 377.819 g/mol
 N (what is this?)  (verify)

Ronifibrate is a fibrate.