Rosoxacin

Title: Rosoxacin
CAS Registry Number: 40034-42-2
CAS Name: 1-Ethyl-1,4-dihydro-4-oxo-7-(4-pyridinyl)-3-quinolinecarboxylic acid
Additional Names: acrosoxacin
Manufacturers' Codes: Win-35213
Trademarks: Eracine (Sanofi Winthrop); Eradacil (Winthrop); Eradacin (Sanofi Winthrop); Winuron (Sanofi Winthrop)
Molecular Formula: C17H14N2O3
Molecular Weight: 294.30
Percent Composition: C 69.38%, H 4.79%, N 9.52%, O 16.31%
Literature References: Quinolone antibacterial. Prepn: G. Y. Lesher, P. M. Carabateas, DE 2224090; eidem, US 3753993 (1972, 1973 both to Sterling). HPLC determn in plasma and urine: M. P. Kullberg et al., J. Chromatogr. 173, 155 (1979). Pharmacological studies: S. Maigaard et al., Urol. Res. 8, 113 (1980); eidem, Invest. Urol. 17, 149 (1979). Clinical study in gonorrhea: B. M. Limson et al., Curr. Ther. Res. 26, 842 (1979).
Properties: Yellow crystals from DMF, mp 290°. Stable in dry heat at 70°. Light sensitive. Solns and suspensions stable at pH 2.0-9.5.
Melting point: mp 290°
Therap-Cat: Antibacterial.
Keywords: Antibacterial (Synthetic); Quinolones and Analogs.
Rostaporfin Rosuvastatin Rotenone Rotraxate Rottlerin

Rosoxacin
Rosoxacin.svg
Systematic (IUPAC) name
1-Ethyl-4-oxo-7-pyridin-4-ylquinoline-3-carboxylic acid
Clinical data
AHFS/Drugs.com International Drug Names
Legal status  ?
Identifiers
CAS number 40034-42-2 YesY
ATC code J01MB01
PubChem CID 287180
DrugBank DB00817
ChemSpider 253208 N
UNII 3Y1OT3J4NW N
KEGG D02305 N
ChEMBL CHEMBL291157 N
Chemical data
Formula C17H14N2O3 
Mol. mass 294.30 g/mol
Physical data
Melt. point 290 °C (554 °F)
 N (what is this?)  (verify)

Rosoxacin (also known as acrosoxacin, tradename Eradacil) is a quinolone antibiotic indicated for the treatment of urinary tract infections and certain sexually transmitted diseases. Rosoxacin is not available in the United States.

It was developed by Sanofi-Synthelabo (now part of sanofi-aventis).

It is classified as first generation.[1]