Sultroponium

Title: Sultroponium
CAS Registry Number: 15130-91-3
CAS Name: endo-(±)-3-(3-Hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(3-sulfopropyl)-8-azoniabicyclo[3.2.1]octane inner salt
Additional Names: 3a-hydroxy-8-(3-sulfopropyl)-1aH,5aH-tropanium hydroxide, (±)-tropate, inner salt; sulfo-betaine of atropine; tropyl tropate sulfo-betaine
Manufacturers' Codes: A-118
Molecular Formula: C20H29NO6S
Molecular Weight: 411.51
Percent Composition: C 58.37%, H 7.10%, N 3.40%, O 23.33%, S 7.79%
Literature References: Anticholinergic. Prepn: Savini et al., Therapie 22, 843 (1967); Wahl, Prod. Probl. Pharm. 25, 260 (1970); Raudnitz et al., BE 672926 (1966) and GB 1082445 (1967).
Properties: Crystals from alc, mp 220° (dec). Sol in water and warm ethanol; insol in ether, acetone, benzene, chloroform. uv max (water): 251.5, 257.5, 263.5 nm.
Melting point: mp 220° (dec)
Absorption maximum: uv max (water): 251.5, 257.5, 263.5 nm
Therap-Cat: Antispasmodic.
Status: This monograph has been retired and is no longer subject to revision or update.
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