Tuberin

Title: Tuberin
CAS Registry Number: 53643-53-1
CAS Name: N-[2-(4-Methoxyphenyl)ethenyl]formamide
Additional Names: N-trans-(p-methoxystyryl)formamide; N-formyl trans-p-methoxystyrylamine
Molecular Formula: C10H11NO2
Molecular Weight: 177.20
Percent Composition: C 67.78%, H 6.26%, N 7.90%, O 18.06%
Literature References: Antitubercular antibiotic isolated from the broth filtrate of Streptomyces amakusaensis: Ohkuma et al., J. Antibiot. 15A, 115 (1962); Sumiki et al., JP 64 7399 (1964 to Inst. Phys. & Chem. Res.), C.A. 62, 8355g (1965). Structure and synthesis: Anzai et al., J. Antibiot. 15A, 110, 117, 123 (1962). Alternate synthesis: I. J. Massey, I. T. Harrison, Chem. Ind. (London) 1977, 920. Biosynthetic studies: K. M. Cable et al., J. Chem. Soc. Perkin Trans. 1 1987, 1593.
Properties: Prisms from benzene, mp 132-133°. Stable in weakly acidic or weakly alkaline solns. uv max (methanol): 219, 285 nm (E1%1cm 870, 1710). Sol in the lower alcohols, ethyl acetate, acetone; moderately sol in carbon tetrachloride, chloroform; sparingly sol in water, benzene. Practically insol in petr ether.
Melting point: mp 132-133°
Absorption maximum: uv max (methanol): 219, 285 nm (E1%1cm 870, 1710)
Derivative Type: Dihydrotuberin
Molecular Formula: C10H13NO2
Molecular Weight: 179.22
Percent Composition: C 67.02%, H 7.31%, N 7.82%, O 17.85%
Properties: Liquid. nD19 1.5349.
Index of refraction: nD19 1.5349
Tubulin Tuftsin Tulathromycin Tulobuterol Tumor Necrosis Factor

Tuberous sclerosis 2
Identifiers
Symbols TSC2 (; LAM; TSC4)
External IDs OMIM: 191092 MGI: 102548 HomoloGene: 462 GeneCards: TSC2 Gene
RNA expression pattern
PBB GE TSC2 215735 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 7249 22084
Ensembl ENSG00000103197 ENSMUSG00000002496
UniProt P49815 Q3UGI8
RefSeq (mRNA) NM_000548 NM_001039363
RefSeq (protein) NP_000539 NP_001034452
Location (UCSC) Chr 16:
2.1 – 2.14 Mb
Chr 17:
24.6 – 24.63 Mb
PubMed search [1] [2]

Tuberin also known as tuberous sclerosis 2 is a protein that in humans is encoded by the TSC2 gene.