Zolimidine

Title: Zolimidine
CAS Registry Number: 1222-57-7
CAS Name: 2-[4-(Methylsulfonyl)phenyl]imidazo[1,2-a]pyridine
Additional Names: zoliridine
Trademarks: Solimidin (Selvi)
Molecular Formula: C14H12N2O2S
Molecular Weight: 272.32
Percent Composition: C 61.75%, H 4.44%, N 10.29%, O 11.75%, S 11.77%
Literature References: Gastroprotective agent. Prepn: GB 991589; L. Almirante et al., US 3318880 (1965, 1967 both to Selvi); eidem, J. Med. Chem. 8, 305 (1965). Metabolism: eidem, Farmaco Ed. Sci. 29, 941 (1974). Series of articles on pharmacology: Panminerva Med. 16, 301-359 (1974). Pharmacokinetics: E. Schraven, D. Trottnow, Arzneim.-Forsch. 26, 213 (1976). Clinical mucopoietic activity: S. Abate et al., Int. J. Tissue React. 4, 319 (1982); M. C. Parodi et al., Scand. J. Gastroenterol. 19, Suppl. 92, 163 (1984). Clinical study: A. Materia et al., Clin. Ter. 97, 183 (1981).
Properties: Crystals, mp 242-244°. LD50 orally in rats: 3710 mg/kg (Almirante, 1967).
Melting point: mp 242-244°
Toxicity data: LD50 orally in rats: 3710 mg/kg (Almirante, 1967)
Therap-Cat: Antiulcerative.
Keywords: Antiulcerative; Cytoprotectant (Gastric).
Zomepirac Zonisamide Zopiclone Zopolrestat Zosuquidar

Zolimidine
Zolimidine.png
Identifiers
CAS number 1222-57-7 YesY
PubChem 14652
ChemSpider 13985 N
KEGG D07075 YesY
ATC code A02BX10
Jmol-3D images Image 1
Properties
Molecular formula C14H12N2O2S
Molar mass 272.32 g/mol
 N (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Zolimidine is a drug used for peptic ulcer and gastroesophageal reflux disease.