alpha-Phenylacetamide

Title: a-Phenylacetamide
CAS Registry Number: 103-81-1
CAS Name: Benzeneacetamide
Additional Names: a-toluamide
Molecular Formula: C8H9NO
Molecular Weight: 135.16
Percent Composition: C 71.09%, H 6.71%, N 10.36%, O 11.84%
Literature References: The amide of phenylacetic acid, not to be confused with N-phenylacetamide which is acetanilide. Prepd by Willgerodt reaction from acetophenone or from styrene. Review and lab procedures: Carmack, Spielman in Org. React. II (New York, 1946) p 83. Has also been prepd by heating the ammonium salt of phenylacetic acid: Menschutkin, Ber. 31, 1429 (1898). Lab procedure from benzyl cyanide: Wenner, Org. Synth. coll. vol. IV, 760 (1963).
Properties: Bimorphous plates, leaflets. mp 155°. Distils in vacuo. Freely sol in alc. Slightly sol in water, ether, benzene.
Melting point: mp 155°
Use: In manuf of penicillin G.
alpha-Phenylbutyramide alpha-Phenylcinnamic Acid alpha-Phenylglycine alpha-Picoline alpha-Pinene